The Production of Cytotoxic T-lymphocytes (CTLs), Step-3
(Go to Step-4)
A resting CD4-helper lymphocyte, by way of its TCR and CD4, binds to the
MHC-II/epitope on the APC which triggers the APC to produce IL-1. The Il-1
binds to receptors on the CD4-helper lymphocyte causing it to become activated.