Immunobiology, Fall 2011

Course  syllabus
Some of these resources were created by Janet M. Decker at the Department of Veterinary Science & Microbiology, University of Arizona.
Powerpoint Lectures:

 

Chapter 1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
Chapter 8
Chapter 9
Chapter 10
Chapter 11
Chapter  12
Chapter  13 Chapter 14
Chapter 15
Chapter 16


 

Study Aids (Quizzes):

 

Study Aid
Study Aid
Study Aid
Study Aid 

Study Aid 1: Humoral

Immunity

Study Aid 2:

B Cell Development

Study Aid 3: Receptor

Signaling


Study Aid 4: T Cell Development
Study Aid 5: T Cell-Mediated Immunity
Study Aid 6: T Cell Receptor Study Aid  7
Study Aid 

 


Cases:

Study Guides
      Study Guide for Exam 1, Study Guide for Exam 2, Study Guide for Exam 3, Study Guide for Exam 4 

Kuby's Web site.
Laboratory
Laboratory Journal Articles: Choice 1 or Choice 2. (Requires Acrobat Reader)
Sites of interest
    - Davidson College: http://www.bio.davidson.edu/courses/Immunology/Bio307.html

Antigen Processing-Processing for MHC-I and MHC-II pathways.
Somatic Recombination - demonstrates how antibodies can bind to so many different epitopes.
MHC I antigen loading - MHC I molecules acquire their antigens for presentation on the cell  surface.
MHC II antigen loading - MHC II  molecules acquire their antigens for presentation on the cell surface.
IP3 and Ca2+ ions as second messengers - shows how ligand binding to a receptor initiates the production of
        IP3 and release of Ca2+ ions from the ER.

B Cell Maturation - shows intracellular and extracellular interactions that illustrate the maturation stages of B
        cells in the bone marrow.

Activation of B Cells with Thymus-Independent (TI) Antigen - shows the role of the B cell receptor and
        co-receptor when challenged with a bacterial or viral anitgen that has many copies of a single epitope.

B Cell Selection - shows how B cells that bind to self-antigen are removed from the repertoire of B cells with
        randomly generated binding specificities. Also shows that non-reactive B cells are permitted to enter general
        circulation.

T Cell Selection - this series of animations shows T Cell development, Positive Selection, and Negative
        Selection. The viewer can choose which process he or she wants to see.

MAPK - an animation which shows how cell surface receptors lead to gene activation. This pathway is called
        the MAP Kinase pathway.

RT-PCR - shows how the method of reverse transcriptase-PCR is performed and some sample data are
        produced.