Impact of body size on biology

Since I was a student of Bill Calder’s in the 1970s, I have maintained an interest in body size effects in biology. In fact, our paper in the Quarterly Review of Biology remains one of my most cited papers. Body size is an excellent tool to decipher what may be considered “constraints” in animal function and design. We have used allometric analyses to gain insights into life history variables such as bird and mammal longevity, home range size and fasting times in mammals. In addition, allometric analyses have provided insights into skeletal muscle structure and function including the function of muscles as tuned locomotor springs in vertebrates. Current research in the lab examine the gigantic muscle protein, titin. It appears that isoforms of this molecule are scaled to body size to provide running mammals with a size-dependant muscle spring.



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Other Interests:

Energetics | Muscles as Springs | Clinical Research