Course
syllabus
Some of these resources were created by Janet M.
Decker at the Department of Veterinary
Science & Microbiology, University of Arizona.
Powerpoint
Lectures:
Chapter
1 |
Chapter
2 |
Chapter
3 |
Chapter
4 |
Chapter
5 |
Chapter
6 |
Chapter
7 |
Chapter
8 |
Chapter
9 |
Chapter
10 |
Chapter
11 |
Chapter 12 |
Chapter 13 | Chapter
14 |
Chapter
15 |
Chapter
16 |
Study Aids (Quizzes):
Study
Aid |
Study
Aid |
Study
Aid |
Study
Aid |
|
Study
Aid 4: T Cell Development |
Study
Aid 5: T Cell-Mediated Immunity |
Study Aid 6: T Cell Receptor | Study Aid 7 |
Study Aid |
Movies:
Lab Pictures
Ab gene recombination 1) Morgan 2) Autumn 3) Stephanie 4) Josh
Complement
Study
Guides:
Study Guide for Exam 1,
Study
Guide for Exam 2,
Study
Guide for Exam 3,
Study
Guide for Exam 4
Kuby's
Web site.
Laboratory
Laboratory
Journal Articles: Choice
1 or Choice
2. (Requires Acrobat Reader)
Sites
of
interest
- Davidson College: http://www.bio.davidson.edu/courses/Immunology/Bio307.html
Antigen Processing-Processing for MHC-I and MHC-II pathways.
Somatic
Recombination
- demonstrates how antibodies can bind to so many different
epitopes.
MHC
I
antigen
loading - MHC I molecules acquire
their
antigens for presentation on the cell surface.
MHC
II
antigen
loading - MHC II molecules
acquire
their antigens for presentation on the cell surface.
IP3
and
Ca2+ ions as second messengers - shows
how
ligand
binding to a receptor initiates the production of
IP3 and release of
Ca2+
ions from the ER.
B
Cell
Maturation
- shows intracellular and extracellular
interactions
that illustrate the maturation stages of B
cells in the bone marrow.
Activation
of B Cells with Thymus-Independent (TI) Antigen - shows
the role of the B cell receptor and
co-receptor when challenged with
a
bacterial
or viral anitgen that has many copies of a single epitope.
B
Cell
Selection
- shows how B cells that bind to
self-antigen
are removed from the repertoire of B cells with
randomly generated
binding
specificities. Also shows that non-reactive B cells are permitted to
enter
general
circulation.
T Cell
Selection
- this series of animations shows T Cell
development,
Positive Selection, and Negative
Selection. The viewer can choose
which
process he or she wants to see.
MAPK
-
an animation which shows how cell surface receptors lead to gene
activation.
This pathway is called
the MAP Kinase pathway.
RT-PCR
-
shows
how the method of reverse transcriptase-PCR is performed and some
sample
data are
produced.