Immunobiology, Fall 2012

Course  syllabus
Some of these resources were created by Janet M. Decker at the Department of Veterinary Science & Microbiology, University of Arizona.
Powerpoint Lectures:

Chapter 1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
Chapter 8
Chapter 9
Chapter 10
Chapter 11
Chapter  12
Chapter  13 Chapter 14
Chapter 15
Chapter 16


Study Aids (Quizzes):

Study Aid
Study Aid
Study Aid
Study Aid 

Study Aid 1: Humoral

Immunity

Study Aid 2:

B Cell Development

Study Aid 3: Receptor

Signaling


Study Aid 4: T Cell Development
Study Aid 5: T Cell-Mediated Immunity
Study Aid 6: T Cell Receptor Study Aid  7
Study Aid 


Movies:                                 Lab Pictures    
Ab gene recombination                           1) Morgan     2) Autumn    3) Stephanie   4) Josh
Complement

Study Guides
Study Guide for Exam 1,
Study Guide for Exam 2,
Study Guide for Exam 3,
Study Guide for Exam 4 

Kuby's Web site.
Laboratory
Laboratory Journal Articles: Choice 1 or Choice 2. (Requires Acrobat Reader)
Sites of interest
    - Davidson College: http://www.bio.davidson.edu/courses/Immunology/Bio307.html

Antigen Processing-Processing for MHC-I and MHC-II pathways.
Somatic Recombination - demonstrates how antibodies can bind to so many different epitopes.
MHC I antigen loading - MHC I molecules acquire their antigens for presentation on the cell  surface.
MHC II antigen loading - MHC II  molecules acquire their antigens for presentation on the cell surface.
IP3 and Ca2+ ions as second messengers - shows how ligand binding to a receptor initiates the production of
        IP3 and release of Ca2+ ions from the ER.

B Cell Maturation - shows intracellular and extracellular interactions that illustrate the maturation stages of B
        cells in the bone marrow.

Activation of B Cells with Thymus-Independent (TI) Antigen - shows the role of the B cell receptor and
        co-receptor when challenged with a bacterial or viral anitgen that has many copies of a single epitope.

B Cell Selection - shows how B cells that bind to self-antigen are removed from the repertoire of B cells with
        randomly generated binding specificities. Also shows that non-reactive B cells are permitted to enter general
        circulation.

T Cell Selection - this series of animations shows T Cell development, Positive Selection, and Negative
        Selection. The viewer can choose which process he or she wants to see.

MAPK - an animation which shows how cell surface receptors lead to gene activation. This pathway is called
        the MAP Kinase pathway.

RT-PCR - shows how the method of reverse transcriptase-PCR is performed and some sample data are
        produced.